I-Dalteparin Sodium
ISITOLO:
IDalteparin Sodium ingeleqembu lemithi ebizwa ngokuthi ama-molecule heparin noma ama-antithrombotic, asiza ukuvimba ukwakheka kwezigaba zegazi ngokunciphisa igazi.
I-Dalteparin Sodium isetshenziselwa ukwelapha ukubekeka kwegazi (venous thromboembolism) nokuvimbela ukuphindeka kwabo. I-venous thromboembolism yisimo lapho ukuqina kwegazi kukhula emilenzeni (i-vein thrombosis ejulile) noma amaphaphu (i-pulmonary embolism), isib ngemuva kokuhlinzwa, ukuphumula kombhede isikhathi eside noma ezigulini ezinezinhlobo ezithile zomdlavuza.
• I-Dalteparin Sodium nayo isetshenziselwa ukwelapha isimo esaziwa ngokuthi isifo se-artery esingazinzile. Ku-coronary artery isifo imithambo ye-coronary (imithambo yegazi iye enhliziyweni) iyavuselelwa futhi incishiswe ngemigqa yama-deposits angamafutha.
Isifo se-coronary artery esingavikeleki sisho ukuthi ingxenye ethile ye-artery ekhulisiwe yomzimba isephuliwe futhi i-wil yakhiwa kuyo, inciphisa ukuhamba kwegazi enhliziyweni. Iziguli ezinalesi simo zingaba ngaphezulu kokuqhubeka nokuba nokuhlaselwa yinhliziyo ngaphandle kokwelashwa ngemithi yokuncipha kwegazi efana ne-Dalteparin Sodium.
IZIMBALI:
I-Dalteparin sodium inokusatshalaliswa kwesisindo esifanele kunazo zonke, futhi inamandla nokuphepha okuyi-anticoagulant. Ukusatshalaliswa kwesisindo se-molecule we-dalteparin sodium yikho okugxilwe kakhulu, umsebenzi we-antithrombotic uqine kakhulu, izingcezwana eziphansi zamangqamuzana zincane, ukugcotshwa kwezidakamizwa kuncane, izingcezu ze-polymer zincane, izinga lokubopha ngamaplatelethi liphansi, izehlakalo ze-HIT uphansi, futhi nengozi yokuphuma kwegazi incane.
Kuphephile kumaqembu akhethekile:
1. I-Dapaparin ukuphela kwe-heparin ephansi yamangqamuzana evunyelwe yi-US FDA yase US ukuze isetshenziswe ngokuphephile kubantu asebekhulile.
I-Dalteparin sodium ukuphela kwe-heparin enesisindo esiphansi engenakho ukuqongelela okuphambili kwiziguli ezinokulimazeka kwe-renal.